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Bacteria rely on classic business model

The bacterium Pseudomonas aeruginosa is one of the most common and dangerous pathogens in hospitals causing severe infections in patients, such as wound infections, pneumonia or meningitis. During the first stage of…


Resistance can spread even without the use of antibiotics

Bacteria are becoming increasingly resistant to common antibiotics. Often, resistance is mediated by resistance genes, which can simply jump from one bacterial population to the next. It’s a common assumption that the…


Immune defense without collateral damage

In the human body’s fight against bacterial pathogens, white blood cells are in the front line. They identify and ingest the invaders, and render them harmless using highly toxic substances. It is important that these…


Bacteria acquire resistance from competitors

The frequent and sometimes careless use of antibiotics leads to an increasingly rapid spread of resistance. Hospitals are a particular hot spot for this. Patients not only introduce a wide variety of pathogens, which may…


Speed controllers for protein production

Proteins perform various jobs in cells, they catalyze thousands of biochemical reactions, relay signals and are required for building cellular structures and transport processes. Within every single cell of our body vast…


BC2 Seminar Spring 2019

BC2 - Basel Computational Biology Seminar Series - Spring Semester 2018 18.02.2019 | Michael Manhart, ETH Zürich Michael Manhart Institute of Integrative Biology, ETH Zürich Zürich, Schweiz High-resolution dynamics of…


Should I stay or should I go: Hospital germ’s dual strategy

In Switzerland, it is not uncommon for a patient to develop an infection during a hospital stay. One reason for this is insufficient hygiene, as shown recently in a study by the Swiss Agency for Therapeutic Products,…


Protected while sleeping: How pathogens survive antibiotic treatment

In recent years, the growing threat of antimicrobial resistance has become widely recognized. However, much less is known about drug-tolerant pathogens, which also complicate the treatment of bacterial infections. These…


Highlights

Biozentrum Highlights Nobel Prize 1978 | Prof. Werner Arber Emeritus page Albert Lasker Basic Medical Research Award 2017 | Prof. Michael N. Hall Research Group Michael Hall Breakthrough Prize in Life Sciences 2014 | Prof.…


New insights into blood vessel formation

Blood vessels run throughout the entire body, delivering nutrients and oxygen through the circulating blood. During vessel formation, cells first form local lumens, which then fuse to form a continuous tubular network. The…