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Single Particles

Applications Single particle analysis is generally used to determine the 3D structure of globular proteins and protein complexes at high resolution. Method Grids holding purified protein samples are plunge-frozen in liquid…


FEI Talos F200C TEM

FEI Talos F200C TEM Configuration 200kV FEG Optics. Cryo-capable with insertable/retactable cryo box. Gatan 626 side-entry cryo holders (LN2 temperature). FEI Ceta 16M Pixel CMOS camera. STEM function. The Talos instrument…


Research Data Management

Where to find information on (image) data management General Research Data Management (RDM) information: Clickable overview to all different aspects of RDM: rdmkit.elixir-europe.org Recommended Metadata for Biological…


Genetic signature boosts protein production during cell division

The production of proteins is the most energy-consuming activity of cells. It needs to be tightly regulated, to ensure efficient use of cellular resources. Researchers led by Prof. Mihaela Zavolan at the Biozentrum have now…


Collective rotations in 2D and in 3D : experiments and theory

Collective rotations in 2D and in 3D : experiments and theory Cells, tissues and organs can rotate spontaneously in vivo and in vitro. These motions are remarkable for their robustness and for their potential functions.…


TFS Titan Krios G4

TFS Titan Krios G4 TEM Configuration The Titan Krios G4 from Thermo Fisher Scientific is a high-end transmission cryo-electron microscope designed for ultimate performance and productivity across a wide range of Life Science…


Projects

Research Projects The central theme of our research is to understand how stochastic interactions of cells and molecules control the functional behaviour of multicellular systems. We specifically focus on how cells interact…


Projects

Research projects We investigate the physiology of bacterial pathogens ( Salmonella , Pseudomonas , Staphylococcus ) in infected rodent and human tissues, focusing on single-cell behavior and potential applications for novel…


Video Publications

Video Engineered kinases as a tool for phosphorylation of selected targets in vivo "The Dawn of Life" Cells into organs. Forscherportrait Prof. Markus Affolter (German) University of Basel: Interview Prof. Dr. Markus…


Invited speakers

Invited speakers Aleksei Aksimentiev (Illinois) Rob Coalson (Pittsburgh) David Cowburn (Einstein) Andreas Dahlin (Chalmers) Cees Dekker (Delft) Chenxiang Lin (Yale) Fabien Montel (Lyon) Siegfried Musser (Texas A&M) Patrick…