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Chronology Part 2

Chronologie 1974 - 2009 2009 Prof. Michael N. Hall Fellow of the American Association for the Advancement of Science Prof. Anne Spang Elected EMBO member Prof. Gottfried Schatz European Prize for Culture in Science by the…


Enigmatic Translons – Animalcules of Molecular Biology?

Enigmatic Translons – Animalcules of Molecular Biology? Ribosome profiling has revealed the extensive utilization of multiple start codons in eukaryotic mRNAs, including in humans. Translation initiation at these start…


The Skin I Live in

The Skin I Live in The forces that shape embryos, and how embryonic cells respond Embryos undergo dramatic morphogenetic movements during development. For example, C. elegans embryos begin as a compact ball of cells and…


Growth control from cells to organisms

Growth control from cells to organisms Imbalance between the growth rate of different organs can amplify to large deviations of their size proportions during development. I will present evidence that, for the pharynx of C.…


New findings pave the way for hearing loss therapies

Hearing loss eventually affects almost everyone: Loud noises or simple aging gradually cause the auditory sensory cells and their synapses in the inner ear to degenerate and die off. The only treatment option is a hearing…


Projects

Stochastic promoter choice during differentiation of neurons Mammals, including humans, have relatively few genes (20-50’000) but millions of neurons with distinct cellular identities. The combinatorial expression of protein…


Single Particles

Applications Single particle analysis is generally used to determine the 3D structure of globular proteins and protein complexes at high resolution. Method Grids holding purified protein samples are plunge-frozen in liquid…


FEI Talos F200C TEM

FEI Talos F200C TEM Configuration 200kV FEG Optics. Cryo-capable with insertable/retactable cryo box. Gatan 626 side-entry cryo holders (LN2 temperature). FEI Ceta 16M Pixel CMOS camera. STEM function. The Talos instrument…


Research Data Management

Where to find information on (image) data management General Research Data Management (RDM) information: Clickable overview to all different aspects of RDM: rdmkit.elixir-europe.org Recommended Metadata for Biological…


Genetic signature boosts protein production during cell division

The production of proteins is the most energy-consuming activity of cells. It needs to be tightly regulated, to ensure efficient use of cellular resources. Researchers led by Prof. Mihaela Zavolan at the Biozentrum have now…