The structure of a protein reveals a lot about its function. This means, the more precisely the three-dimensional protein structure is known, the better the conclusions on its function can be drawn. Using NMR spectroscopy,…
Cells proliferate by dividing repeatedly. Each cell division produces two daughter cells, which must first grow to a certain size before they can divide, too. This requires an increased production of cell components,…
The WHO calls the creeping and rapidly growing number of antibiotic-resistant bacteria a “silent pandemic”. The crisis is aggravated by the fact that hardly any new drugs have come onto the market in recent decades. Even…
Misfolded proteins are non-functional and cause cell damage. In order to prevent this, there is a whole arsenal of proteins – called chaperones – that assist with folding and carry out quality control. In the bacterium…
Parkinson's disease is one of the most common neurodegenerative disorders. In Switzerland, about 15,000 people are affected. Because of the worldwide rise in life expectancy, a rapid increase in Parkinson's cases is expected…
The opening of the new Swiss High-field NMR Facility was attended by high-ranking representatives of the three participating universities, invited guests from academia and industry along with scientists working in the fields…
A number of pathogens protect themselves with an outer membrane that makes it difficult to combat them with antibiotics. In addition, the widespread use of antibiotics promotes the development of resistant bacteria. In…
An increasing number of bacterial pathogens are resistant to antibiotics. And the most dangerous pathogens share a common feature: a double membrane that is difficult to penetrate. Even when antibiotic agents are able to…
When infecting a host, pathogens not only need to evade the immune defense but also to survive diverse living conditions, such as the acidic conditions in the stomach or the salty intestinal environment. Gram negative…
What questions arise in day-to-day scientific research? What is it like to work as a scientist? And how does a research group work? The opportunity to get to the bottom of these questions, to actively participate in everyday…
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