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Relay station in the brain controls our movements

Whether we move our arms, legs or the entire body, every movement is centrally controlled by our brain. Different brain regions and neuronal networks play an essential role in this process. This includes the Substantia…


ERC Advanced Grant for Alex Schier

The ERC Advanced Grants, which are awarded by the European Research Council (ERC), are among the most prestigious and coveted grants in basic research: only 10 percent of application submissions are successful. The grants…


Blood must flow: How pushing and pulling forces shape our blood vessels

To supply the body with blood, billions of cells must be organized into a highly branched vascular network. This process of blood vessel formation relies on the creation of hollow tubes, which contain a continuous lumen,…


Precise Genetics: New CRISPR method enables efficient DNA modification

With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This…


The enemy within: How pathogens spread unrecognized in the body

The inside of a cell provides as a hiding place for various pathogens. By residing in the cell, the bacteria can evade the immune response and spread within the body. Among these invaders are Burkholderia bacteria, including…


Breast cancer: New way for tumor cells to escape self-destruction

Breast cancer is by far the most frequent type of cancer affecting women and a leading cause of death, despite advances in its detection and treatment. There are different forms of breast cancer and the causes are just as…


Sabotage attack: How a bacterial protein tricks our innate immune response

When our innate immune system detects a pathogen it mounts a potent inflammatory response that has the capacity to contain and eliminate the infection, but typically also causes significant damage to the inflamed tissue.…


Marek Basler receives prestigious "ERC Consolidator Grant"

Since his time as a postdoctoral fellow at Harvard Medical School in Boston, Marek Basler has been fascinated by a tiny bacterial injection apparatus, the so-called type 6 secretion system (T6SS). This nanomachine works like…


Magnesium deprivation stops pathogen growth

When pathogens infect an organism, the defense system immediately starts to fight the bacteria. To escape the patrolling immune cells, some bacteria invade and replicate inside host cells. However, the host has developed…


Reaching and Grasping – Learning fine motor coordination changes the brain

Simply grasping a coffee cup needs fine motor coordination with the highest precision. This required performance of the brain is an ability that can also be learned and trained. Prof. Kelly Tan's research group at the…